P425-0257 Screening compound: N-(3-chloro-4-methoxyphenyl)-5H,6H,8H-imidazo[2,1-c][1,4]thiazine-2-carboxamide

P425-0257 Screening compound: N-(3-chloro-4-methoxyphenyl)-5H,6H,8H-imidazo[2,1-c][1,4]thiazine-2-carboxamide
P425-0257 Screening compound: N-(3-chloro-4-methoxyphenyl)-5H,6H,8H-imidazo[2,1-c][1,4]thiazine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P425-0257
N-(3-chloro-4-methoxyphenyl)-5H,6H,8H-imidazo[2,1-c][1,4]thiazine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P425-0257

Molecular Formula

C14H14ClN3O2S (C14 H14 ClN3 O2 S)

Compound Name

N-(3-chloro-4-methoxyphenyl)-5H,6H,8H-imidazo[2,1-c][1,4]thiazine-2-carboxamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-5H6H8H-imidazo[21-c][14]thiazine-2-carboxamide

SMILES

COc(ccc(NC(c1cn(CCSC2)c2n1)=O)c1)c1Cl

InChI

InChI=1S/C14H14ClN3O2S/c1-20-12-3-2-9(6-10(12)15)16-14(19)11-7-18-4-5-21-8-13(18)17-11/h2-3,6-7H,4-5,8H2,1H3,(H,16,19)

InChI Key

TVDIQNYTSJIYNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574213

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.8

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.484

Distribution Coefficient, logD

2.483

Water Solubility, LogSw

-3.34

Polar Surface Area

43.836

Acid Dissociation Constant (pKa)

10.00

Base Dissociation Constant (pKb)

2.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

P425-0257 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P425-0257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P425-0257?
Check Price and Availability of P425-0257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P425-0257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P425-0257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P425-0257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P425-0257 available by request