P431-1893 Screening compound: 2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide

P431-1893 Screening compound: 2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide
P431-1893 Screening compound: 2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P431-1893
2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P431-1893

Molecular Formula

C20H24N6O2S (C20 H24 N6 O2 S)

Compound Name

2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide

IUPAC name

2-phenyl-N-{1-[5-(piperidin-1-yl)pyrimidin-2-yl]-1H-pyrazol-4-yl}ethane-1-sulfonamide

SMILES

O=S(CCc1ccccc1)(Nc1cn(-c(nc2)ncc2N2CCCCC2)nc1)=O

InChI

InChI=1S/C20H24N6O2S/c27-29(28,12-9-17-7-3-1-4-8-17)24-18-13-23-26(16-18)20-21-14-19(15-22-20)25-10-5-2-6-11-25/h1,3-4,7-8,13-16,24H,2,5-6,9-12H2

InChI Key

AVJZGFJTQBXAGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574579

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.366

Distribution Coefficient, logD

2.277

Water Solubility, LogSw

-2.69

Polar Surface Area

78.867

Acid Dissociation Constant (pKa)

8.05

Base Dissociation Constant (pKb)

3.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

P431-1893 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P431-1893 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P431-1893?
Check Price and Availability of P431-1893, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P431-1893 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P431-1893
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P431-1893
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P431-1893 available by request