P432-0176 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-4-(dimethylamino)-5,7-dimethylpyrido[2,3-d]pyrimidine-2-carboxamide

P432-0176 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-4-(dimethylamino)-5,7-dimethylpyrido[2,3-d]pyrimidine-2-carboxamide
P432-0176 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-4-(dimethylamino)-5,7-dimethylpyrido[2,3-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P432-0176
N-(2H-1,3-benzodioxol-5-yl)-4-(dimethylamino)-5,7-dimethylpyrido[2,3-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P432-0176

Molecular Formula

C19H19N5O3 (C19 H19 N5 O3)

Compound Name

N-(2H-1,3-benzodioxol-5-yl)-4-(dimethylamino)-5,7-dimethylpyrido[2,3-d]pyrimidine-2-carboxamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-4-(dimethylamino)-57-dimethylpyrido[23-d]pyrimidine-2-carboxamide

SMILES

Cc1c(c(N(C)C)nc(C(Nc(cc2)cc3c2OCO3)=O)n2)c2nc(C)c1

InChI

InChI=1S/C19H19N5O3/c1-10-7-11(2)20-16-15(10)18(24(3)4)23-17(22-16)19(25)21-12-5-6-13-14(8-12)27-9-26-13/h5-8H,9H2,1-4H3,(H,21,25)

InChI Key

QYQVRGNQBGFJDE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574618

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.290

Distribution Coefficient, logD

3.290

Water Solubility, LogSw

-3.52

Polar Surface Area

71.217

Acid Dissociation Constant (pKa)

11.07

Base Dissociation Constant (pKb)

3.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

P432-0176 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P432-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P432-0176?
Check Price and Availability of P432-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P432-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P432-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P432-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P432-0176 available by request