P432-0405 Screening compound: 5,7-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

P432-0405 Screening compound: 5,7-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidine-2-carboxamide
P432-0405 Screening compound: 5,7-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P432-0405
5,7-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P432-0405

Molecular Formula

C21H24N6O (C21 H24 N6 O)

Compound Name

5,7-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

IUPAC name

57-dimethyl-N-[1-(pyridin-2-yl)ethyl]-4-(pyrrolidin-1-yl)pyrido[23-d]pyrimidine-2-carboxamide

SMILES

CC(c1ncccc1)NC(c1nc2nc(C)cc(C)c2c(N2CCCC2)n1)=O

InChI

InChI=1S/C21H24N6O/c1-13-12-14(2)23-18-17(13)20(27-10-6-7-11-27)26-19(25-18)21(28)24-15(3)16-8-4-5-9-22-16/h4-5,8-9,12,15H,6-7,10-11H2,1-3H3,(H,24,28)/t15-/m0/s1

InChI Key

VRXUNWLOCQVSRY-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27574693

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.050

Distribution Coefficient, logD

3.047

Water Solubility, LogSw

-3.30

Polar Surface Area

64.649

Acid Dissociation Constant (pKa)

12.64

Base Dissociation Constant (pKb)

5.28

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

P432-0405 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with P432-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P432-0405?
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What is the minimum amount of P432-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P432-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P432-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P432-0405 available by request