P432-0441 Screening compound: 1'-[5,7-dimethyl-4-(piperidin-1-yl)pyrido[2,3-d]pyrimidine-2-carbonyl]-1,4'-bipiperidine

P432-0441 Screening compound: 1'-[5,7-dimethyl-4-(piperidin-1-yl)pyrido[2,3-d]pyrimidine-2-carbonyl]-1,4'-bipiperidine
P432-0441 Screening compound: 1'-[5,7-dimethyl-4-(piperidin-1-yl)pyrido[2,3-d]pyrimidine-2-carbonyl]-1,4'-bipiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P432-0441
1'-[5,7-dimethyl-4-(piperidin-1-yl)pyrido[2,3-d]pyrimidine-2-carbonyl]-1,4'-bipiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P432-0441

Molecular Formula

C25H36N6O (C25 H36 N6 O)

Compound Name

1'-[5,7-dimethyl-4-(piperidin-1-yl)pyrido[2,3-d]pyrimidine-2-carbonyl]-1,4'-bipiperidine

IUPAC name

1'-[57-dimethyl-4-(piperidin-1-yl)pyrido[23-d]pyrimidine-2-carbonyl]-14'-bipiperidine

SMILES

Cc1c(c(N2CCCCC2)nc(C(N(CC2)CCC2N2CCCCC2)=O)n2)c2nc(C)c1

InChI

InChI=1S/C25H36N6O/c1-18-17-19(2)26-22-21(18)24(30-13-7-4-8-14-30)28-23(27-22)25(32)31-15-9-20(10-16-31)29-11-5-3-6-12-29/h17,20H,3-16H2,1-2H3

InChI Key

JOCOWMJPOYXSNG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.234

Distribution Coefficient, logD

0.794

Water Solubility, LogSw

-4.29

Polar Surface Area

51.400

Acid Dissociation Constant (pKa)

21.49

Base Dissociation Constant (pKb)

10.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.00

P432-0441 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P432-0441 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P432-0441?
Check Price and Availability of P432-0441, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P432-0441 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P432-0441
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P432-0441
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P432-0441 available by request