P432-0780 Screening compound: 5,7-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

P432-0780 Screening compound: 5,7-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide
P432-0780 Screening compound: 5,7-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P432-0780
5,7-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P432-0780

Molecular Formula

C17H23N5OS (C17 H23 N5 OS)

Compound Name

5,7-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

IUPAC name

57-dimethyl-N-(propan-2-yl)-4-(thiomorpholin-4-yl)pyrido[23-d]pyrimidine-2-carboxamide

SMILES

CC(C)NC(c1nc2nc(C)cc(C)c2c(N2CCSCC2)n1)=O

InChI

InChI=1S/C17H23N5OS/c1-10(2)18-17(23)15-20-14-13(11(3)9-12(4)19-14)16(21-15)22-5-7-24-8-6-22/h9-10H,5-8H2,1-4H3,(H,18,23)

InChI Key

TXXSCJRQBKSEKO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.904

Distribution Coefficient, logD

2.901

Water Solubility, LogSw

-3.29

Polar Surface Area

55.318

Acid Dissociation Constant (pKa)

15.19

Base Dissociation Constant (pKb)

5.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.90

P432-0780 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Nervous system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P432-0780 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P432-0780?
Check Price and Availability of P432-0780, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P432-0780 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P432-0780
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P432-0780
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P432-0780 available by request