P432-0807 Screening compound: N-butyl-N,5,7-trimethyl-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

P432-0807 Screening compound: N-butyl-N,5,7-trimethyl-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide
P432-0807 Screening compound: N-butyl-N,5,7-trimethyl-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P432-0807
N-butyl-N,5,7-trimethyl-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P432-0807

Molecular Formula

C19H27N5OS (C19 H27 N5 OS)

Compound Name

N-butyl-N,5,7-trimethyl-4-(thiomorpholin-4-yl)pyrido[2,3-d]pyrimidine-2-carboxamide

IUPAC name

N-butyl-N57-trimethyl-4-(thiomorpholin-4-yl)pyrido[23-d]pyrimidine-2-carboxamide

SMILES

CCCCN(C)C(c1nc2nc(C)cc(C)c2c(N2CCSCC2)n1)=O

InChI

InChI=1S/C19H27N5OS/c1-5-6-7-23(4)19(25)17-21-16-15(13(2)12-14(3)20-16)18(22-17)24-8-10-26-11-9-24/h12H,5-11H2,1-4H3

InChI Key

HYXJOBQNWVEJFI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27574807

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.382

Distribution Coefficient, logD

3.370

Water Solubility, LogSw

-3.67

Polar Surface Area

48.059

Acid Dissociation Constant (pKa)

21.88

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.90

P432-0807 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with P432-0807 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P432-0807?
Check Price and Availability of P432-0807, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P432-0807 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P432-0807
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P432-0807
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P432-0807 available by request