P433-0558 Screening compound: 8-[3-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

P433-0558 Screening compound: 8-[3-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane
P433-0558 Screening compound: 8-[3-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P433-0558
8-[3-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P433-0558

Molecular Formula

C21H20ClN3O3 (C21 H20 ClN3 O3)

Compound Name

8-[3-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[3-(4-chlorophenyl)imidazo[12-a]pyridine-2-carbonyl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1c(-c(cc2)ccc2Cl)n(cccc2)c2n1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C21H20ClN3O3/c22-16-6-4-15(5-7-16)19-18(23-17-3-1-2-10-25(17)19)20(26)24-11-8-21(9-12-24)27-13-14-28-21/h1-7,10H,8-9,11-14H2

InChI Key

CKJDSFJMHBWHDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021725

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.760

Distribution Coefficient, logD

2.760

Water Solubility, LogSw

-3.45

Polar Surface Area

39.209

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

4.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P433-0558 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P433-0558 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P433-0558?
Check Price and Availability of P433-0558, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P433-0558 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P433-0558
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P433-0558
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P433-0558 available by request