P433-0649 Screening compound: 3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[1,2-a]pyridine-2-carboxamide

P433-0649 Screening compound: 3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[1,2-a]pyridine-2-carboxamide
P433-0649 Screening compound: 3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[1,2-a]pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P433-0649
3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[1,2-a]pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P433-0649

Molecular Formula

C21H24ClN5O (C21 H24 ClN5 O)

Compound Name

3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[1,2-a]pyridine-2-carboxamide

IUPAC name

3-(4-chlorophenyl)-N-[2-(4-methylpiperazin-1-yl)ethyl]imidazo[12-a]pyridine-2-carboxamide

SMILES

CN1CCN(CCNC(c2c(-c(cc3)ccc3Cl)n(cccc3)c3n2)=O)CC1

InChI

InChI=1S/C21H24ClN5O/c1-25-12-14-26(15-13-25)11-9-23-21(28)19-20(16-5-7-17(22)8-6-16)27-10-3-2-4-18(27)24-19/h2-8,10H,9,11-15H2,1H3,(H,23,28)

InChI Key

VLCJEDBIEBKZQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021737

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.91

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.124

Distribution Coefficient, logD

1.456

Water Solubility, LogSw

-3.19

Polar Surface Area

39.838

Acid Dissociation Constant (pKa)

14.14

Base Dissociation Constant (pKb)

7.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P433-0649 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with P433-0649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P433-0649?
Check Price and Availability of P433-0649, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P433-0649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P433-0649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P433-0649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P433-0649 available by request