P433-0667 Screening compound: 8-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

P433-0667 Screening compound: 8-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane
P433-0667 Screening compound: 8-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P433-0667
8-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P433-0667

Molecular Formula

C21H20FN3O3 (C21 H20 FN3 O3)

Compound Name

8-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[3-(4-fluorophenyl)imidazo[12-a]pyridine-2-carbonyl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1c(-c(cc2)ccc2F)n(cccc2)c2n1)N(CC1)CCC11OCCO1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.195

Distribution Coefficient, logD

2.194

Water Solubility, LogSw

-2.35

Polar Surface Area

39.209

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

4.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P433-0667 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P433-0667 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P433-0667?
Check Price and Availability of P433-0667, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P433-0667 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P433-0667
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P433-0667
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P433-0667 available by request