P433-0766 Screening compound: 1-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine

P433-0766 Screening compound: 1-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine
P433-0766 Screening compound: 1-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P433-0766
1-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P433-0766

Molecular Formula

C21H23FN4O (C21 H23 FN4 O)

Compound Name

1-[3-(4-fluorophenyl)imidazo[1,2-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine

IUPAC name

1-[3-(4-fluorophenyl)imidazo[12-a]pyridine-2-carbonyl]-4-(propan-2-yl)piperazine

SMILES

CC(C)N(CC1)CCN1C(c1c(-c(cc2)ccc2F)n(cccc2)c2n1)=O

InChI

InChI=1S/C21H23FN4O/c1-15(2)24-11-13-25(14-12-24)21(27)19-20(16-6-8-17(22)9-7-16)26-10-4-3-5-18(26)23-19/h3-10,15H,11-14H2,1-2H3

InChI Key

QUMBIEACPDKTNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29021756

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.786

Distribution Coefficient, logD

2.450

Water Solubility, LogSw

-3.02

Polar Surface Area

28.636

Acid Dissociation Constant (pKa)

28.10

Base Dissociation Constant (pKb)

7.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P433-0766 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P433-0766 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P433-0766?
Check Price and Availability of P433-0766, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P433-0766 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P433-0766
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P433-0766
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P433-0766 available by request