P435-0202 Screening compound: 3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine

P435-0202 Screening compound: 3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine
P435-0202 Screening compound: 3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound P435-0202
3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P435-0202

Molecular Formula

C21H26N4O3S (C21 H26 N4 O3 S)

Compound Name

3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine

IUPAC name

3-{4-[5-methyl-4-(pyrrolidine-1-carbonyl)-13-oxazol-2-yl]piperidine-1-carbonyl}-2-(methylsulfanyl)pyridine

SMILES

Cc1c(C(N2CCCC2)=O)nc(C(CC2)CCN2C(c2cccnc2SC)=O)o1

InChI

InChI=1S/C21H26N4O3S/c1-14-17(21(27)24-10-3-4-11-24)23-18(28-14)15-7-12-25(13-8-15)20(26)16-6-5-9-22-19(16)29-2/h5-6,9,15H,3-4,7-8,10-13H2,1-2H3

InChI Key

DXNWLDXSQUQEOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575003

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.259

Distribution Coefficient, logD

2.259

Water Solubility, LogSw

-2.73

Polar Surface Area

60.707

Acid Dissociation Constant (pKa)

26.16

Base Dissociation Constant (pKb)

2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.40

P435-0202 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P435-0202 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P435-0202?
Check Price and Availability of P435-0202, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P435-0202 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P435-0202
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P435-0202
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P435-0202 available by request