P435-0259 Screening compound: (5-methyl-2-{1-[(5-methyl-2-thienyl)carbonyl]-4-piperidyl}-1,3-oxazol-4-yl)(1-pyrrolidinyl)methanone

P435-0259 Screening compound: (5-methyl-2-{1-[(5-methyl-2-thienyl)carbonyl]-4-piperidyl}-1,3-oxazol-4-yl)(1-pyrrolidinyl)methanone
P435-0259 Screening compound: (5-methyl-2-{1-[(5-methyl-2-thienyl)carbonyl]-4-piperidyl}-1,3-oxazol-4-yl)(1-pyrrolidinyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P435-0259
(5-methyl-2-{1-[(5-methyl-2-thienyl)carbonyl]-4-piperidyl}-1,3-oxazol-4-yl)(1-pyrrolidinyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P435-0259

Molecular Formula

C20H25N3O3S (C20 H25 N3 O3 S)

Compound Name

(5-methyl-2-{1-[(5-methyl-2-thienyl)carbonyl]-4-piperidyl}-1,3-oxazol-4-yl)(1-pyrrolidinyl)methanone

IUPAC name

4-[5-methyl-4-(pyrrolidine-1-carbonyl)-13-oxazol-2-yl]-1-(5-methylthiophene-2-carbonyl)piperidine

SMILES

Cc1ccc(C(N(CC2)CCC2c2nc(C(N3CCCC3)=O)c(C)o2)=O)s1

InChI

InChI=1S/C20H25N3O3S/c1-13-5-6-16(27-13)19(24)23-11-7-15(8-12-23)18-21-17(14(2)26-18)20(25)22-9-3-4-10-22/h5-6,15H,3-4,7-12H2,1-2H3

InChI Key

QNTYAXJUSFSZNK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575032

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.286

Distribution Coefficient, logD

3.286

Water Solubility, LogSw

-3.12

Polar Surface Area

52.546

Acid Dissociation Constant (pKa)

26.24

Base Dissociation Constant (pKb)

-1.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.00

P435-0259 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P435-0259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P435-0259?
Check Price and Availability of P435-0259, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P435-0259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P435-0259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P435-0259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P435-0259 available by request