P435-1145 Screening compound: N-(2,3-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carboxamide

P435-1145 Screening compound: N-(2,3-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carboxamide
P435-1145 Screening compound: N-(2,3-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P435-1145
N-(2,3-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P435-1145

Molecular Formula

C24H30N4O3 (C24 H30 N4 O3)

Compound Name

N-(2,3-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-1,3-oxazol-2-yl]piperidine-1-carboxamide

IUPAC name

N-(23-dihydro-1H-inden-5-yl)-4-[5-methyl-4-(pyrrolidine-1-carbonyl)-13-oxazol-2-yl]piperidine-1-carboxamide

SMILES

Cc1c(C(N2CCCC2)=O)nc(C(CC2)CCN2C(Nc2cc(CCC3)c3cc2)=O)o1

InChI

InChI=1S/C24H30N4O3/c1-16-21(23(29)27-11-2-3-12-27)26-22(31-16)18-9-13-28(14-10-18)24(30)25-20-8-7-17-5-4-6-19(17)15-20/h7-8,15,18H,2-6,9-14H2,1H3,(H,25,30)

InChI Key

NWYYCNLWLPYORO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575367

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.687

Distribution Coefficient, logD

3.687

Water Solubility, LogSw

-3.76

Polar Surface Area

60.635

Acid Dissociation Constant (pKa)

14.11

Base Dissociation Constant (pKb)

-0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

P435-1145 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with P435-1145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P435-1145?
Check Price and Availability of P435-1145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P435-1145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P435-1145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P435-1145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P435-1145 available by request