P435-1234 Screening compound: N~1~-cyclohexyl-4-[5-methyl-4-(morpholinocarbonyl)-1,3-oxazol-2-yl]tetrahydro-1(2H)-pyridinecarboxamide

P435-1234 Screening compound: N~1~-cyclohexyl-4-[5-methyl-4-(morpholinocarbonyl)-1,3-oxazol-2-yl]tetrahydro-1(2H)-pyridinecarboxamide
P435-1234 Screening compound: N~1~-cyclohexyl-4-[5-methyl-4-(morpholinocarbonyl)-1,3-oxazol-2-yl]tetrahydro-1(2H)-pyridinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P435-1234
N~1~-cyclohexyl-4-[5-methyl-4-(morpholinocarbonyl)-1,3-oxazol-2-yl]tetrahydro-1(2H)-pyridinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P435-1234

Molecular Formula

C21H32N4O4 (C21 H32 N4 O4)

Compound Name

N~1~-cyclohexyl-4-[5-methyl-4-(morpholinocarbonyl)-1,3-oxazol-2-yl]tetrahydro-1(2H)-pyridinecarboxamide

IUPAC name

N-cyclohexyl-4-[5-methyl-4-(morpholine-4-carbonyl)-13-oxazol-2-yl]piperidine-1-carboxamide

SMILES

Cc1c(C(N2CCOCC2)=O)nc(C(CC2)CCN2C(NC2CCCCC2)=O)o1

InChI

InChI=1S/C21H32N4O4/c1-15-18(20(26)24-11-13-28-14-12-24)23-19(29-15)16-7-9-25(10-8-16)21(27)22-17-5-3-2-4-6-17/h16-17H,2-14H2,1H3,(H,22,27)

InChI Key

MGJZHJZMCKCCGS-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.329

Distribution Coefficient, logD

2.329

Water Solubility, LogSw

-2.35

Polar Surface Area

68.939

Acid Dissociation Constant (pKa)

16.99

Base Dissociation Constant (pKb)

2.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

76.19

P435-1234 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with P435-1234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P435-1234?
Check Price and Availability of P435-1234, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P435-1234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P435-1234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P435-1234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P435-1234 available by request