P435-1837 Screening compound: {5-METHYL-2-[1-({5-METHYL-4-[(3,4,5-TRIMETHYL-1H-PYRAZOL-1-YL)METHYL]-3-ISOXAZOLYL}CARBONYL)-4-PIPERIDYL]-1,3-OXAZOL-4-YL}(1-PYRROLIDINYL)METHANONE

P435-1837 Screening compound: {5-METHYL-2-[1-({5-METHYL-4-[(3,4,5-TRIMETHYL-1H-PYRAZOL-1-YL)METHYL]-3-ISOXAZOLYL}CARBONYL)-4-PIPERIDYL]-1,3-OXAZOL-4-YL}(1-PYRROLIDINYL)METHANONE
P435-1837 Screening compound: {5-METHYL-2-[1-({5-METHYL-4-[(3,4,5-TRIMETHYL-1H-PYRAZOL-1-YL)METHYL]-3-ISOXAZOLYL}CARBONYL)-4-PIPERIDYL]-1,3-OXAZOL-4-YL}(1-PYRROLIDINYL)METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound P435-1837
{5-METHYL-2-[1-({5-METHYL-4-[(3,4,5-TRIMETHYL-1H-PYRAZOL-1-YL)METHYL]-3-ISOXAZOLYL}CARBONYL)-4-PIPERIDYL]-1,3-OXAZOL-4-YL}(1-PYRROLIDINYL)METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P435-1837

Molecular Formula

C26H34N6O4 (C26 H34 N6 O4)

Compound Name

{5-METHYL-2-[1-({5-METHYL-4-[(3,4,5-TRIMETHYL-1H-PYRAZOL-1-YL)METHYL]-3-ISOXAZOLYL}CARBONYL)-4-PIPERIDYL]-1,3-OXAZOL-4-YL}(1-PYRROLIDINYL)METHANONE

IUPAC name

n/a

SMILES

Cc1c(C)n(Cc2c(C)onc2C(N(CC2)CCC2c2nc(C(N3CCCC3)=O)c(C)o2)=O)nc1C

InChI

InChI=1S/C26H34N6O4/c1-15-16(2)28-32(17(15)3)14-21-18(4)36-29-23(21)26(34)31-12-8-20(9-13-31)24-27-22(19(5)35-24)25(33)30-10-6-7-11-30/h20H,6-14H2,1-5H3

InChI Key

IOZKZZBMBKJQGA-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.235

Distribution Coefficient, logD

2.234

Water Solubility, LogSw

-2.04

Polar Surface Area

88.041

Acid Dissociation Constant (pKa)

24.19

Base Dissociation Constant (pKb)

4.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

P435-1837 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P435-1837 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P435-1837?
Check Price and Availability of P435-1837, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P435-1837 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P435-1837
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P435-1837
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P435-1837 available by request