P492-0922 Screening compound: 3-[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

P492-0922 Screening compound: 3-[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one
P492-0922 Screening compound: 3-[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P492-0922
3-[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P492-0922

Molecular Formula

C22H18N4O2S2 (C22 H18 N4 O2 S2)

Compound Name

3-[2-oxo-2-(1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

IUPAC name

3-[2-oxo-2-(1234-tetrahydroquinolin-1-yl)ethyl]-5-[4-(thiophen-2-yl)-13-thiazol-2-yl]-34-dihydropyrimidin-4-one

SMILES

O=C(CN(C=NC=C1c2nc(-c3cccs3)cs2)C1=O)N(CCC1)c2c1cccc2

InChI

InChI=1S/C22H18N4O2S2/c27-20(26-9-3-6-15-5-1-2-7-18(15)26)12-25-14-23-11-16(22(25)28)21-24-17(13-30-21)19-8-4-10-29-19/h1-2,4-5,7-8,10-11,13-14H,3,6,9,12H2

InChI Key

BFRIJOKJPMULMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575964

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.275

Distribution Coefficient, logD

3.275

Water Solubility, LogSw

-3.42

Polar Surface Area

52.413

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

P492-0922 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with P492-0922 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P492-0922?
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What is the minimum amount of P492-0922 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P492-0922
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P492-0922
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P492-0922 available by request