P492-1757 Screening compound: 2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P492-1757 Screening compound: 2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P492-1757 Screening compound: 2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P492-1757
2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P492-1757

Molecular Formula

C16H14N4O2S (C16 H14 N4 O2 S)

Compound Name

2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

2-[2-methyl-6-oxo-5-(4-phenyl-13-thiazol-2-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

CC(N1CC(N)=O)=NC=C(c2nc(-c3ccccc3)cs2)C1=O

InChI

InChI=1S/C16H14N4O2S/c1-10-18-7-12(16(22)20(10)8-14(17)21)15-19-13(9-23-15)11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H2,17,21)

InChI Key

PIIWMDFCAYLGOR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575986

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.618

Distribution Coefficient, logD

1.618

Water Solubility, LogSw

-2.22

Polar Surface Area

67.496

Acid Dissociation Constant (pKa)

15.64

Base Dissociation Constant (pKb)

4.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

P492-1757 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiparasite Library (23996 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P492-1757 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P492-1757?
Check Price and Availability of P492-1757, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P492-1757 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P492-1757
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P492-1757
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P492-1757 available by request