P492-1789 Screening compound: N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P492-1789 Screening compound: N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P492-1789 Screening compound: N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P492-1789
N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P492-1789

Molecular Formula

C24H22N4O3S (C24 H22 N4 O3 S)

Compound Name

N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(2-methoxy-5-methylphenyl)-2-[2-methyl-6-oxo-5-(4-phenyl-13-thiazol-2-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

Cc(cc1)cc(NC(CN(C(C)=NC=C2c3nc(-c4ccccc4)cs3)C2=O)=O)c1OC

InChI

InChI=1S/C24H22N4O3S/c1-15-9-10-21(31-3)19(11-15)26-22(29)13-28-16(2)25-12-18(24(28)30)23-27-20(14-32-23)17-7-5-4-6-8-17/h4-12,14H,13H2,1-3H3,(H,26,29)

InChI Key

YJGPZVWOXPNJLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575994

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.811

Distribution Coefficient, logD

3.811

Water Solubility, LogSw

-3.96

Polar Surface Area

63.919

Acid Dissociation Constant (pKa)

11.53

Base Dissociation Constant (pKb)

3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

P492-1789 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P492-1789 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P492-1789?
Check Price and Availability of P492-1789, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P492-1789 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P492-1789
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P492-1789
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P492-1789 available by request