P501-0220 Screening compound: N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

P501-0220 Screening compound: N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide
P501-0220 Screening compound: N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P501-0220
N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P501-0220

Molecular Formula

C22H26N4O3 (C22 H26 N4 O3)

Compound Name

N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

IUPAC name

N-(4-methoxy-2-methylphenyl)-1'-methyl-4'-oxo-3'4'-dihydro-1'H-spiro[piperidine-42'-quinazoline]-1-carboxamide

SMILES

Cc(cc(cc1)OC)c1NC(N(CC1)CCC1(N1)N(C)c(cccc2)c2C1=O)=O

InChI

InChI=1S/C22H26N4O3/c1-15-14-16(29-3)8-9-18(15)23-21(28)26-12-10-22(11-13-26)24-20(27)17-6-4-5-7-19(17)25(22)2/h4-9,14H,10-13H2,1-3H3,(H,23,28)(H,24,27)

InChI Key

BNCFEOKABRVKDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27576897

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.695

Distribution Coefficient, logD

2.695

Water Solubility, LogSw

-3.36

Polar Surface Area

59.306

Acid Dissociation Constant (pKa)

13.46

Base Dissociation Constant (pKb)

-0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

P501-0220 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P501-0220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P501-0220?
Check Price and Availability of P501-0220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P501-0220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P501-0220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P501-0220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P501-0220 available by request