P510-0221 Screening compound: [1-(6-morpholino-4-pyrimidinyl)-4-piperidyl](1,4-thiazinan-4-yl)methanone

P510-0221 Screening compound: [1-(6-morpholino-4-pyrimidinyl)-4-piperidyl](1,4-thiazinan-4-yl)methanone
P510-0221 Screening compound: [1-(6-morpholino-4-pyrimidinyl)-4-piperidyl](1,4-thiazinan-4-yl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P510-0221
[1-(6-morpholino-4-pyrimidinyl)-4-piperidyl](1,4-thiazinan-4-yl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P510-0221

Molecular Formula

C18H27N5O2S (C18 H27 N5 O2 S)

Compound Name

[1-(6-morpholino-4-pyrimidinyl)-4-piperidyl](1,4-thiazinan-4-yl)methanone

IUPAC name

4-{6-[4-(thiomorpholine-4-carbonyl)piperidin-1-yl]pyrimidin-4-yl}morpholine

SMILES

O=C(C(CC1)CCN1c1ncnc(N2CCOCC2)c1)N1CCSCC1

InChI

InChI=1S/C18H27N5O2S/c24-18(23-7-11-26-12-8-23)15-1-3-21(4-2-15)16-13-17(20-14-19-16)22-5-9-25-10-6-22/h13-15H,1-12H2

InChI Key

RFWKUQHWRLVFBJ-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.109

Distribution Coefficient, logD

2.105

Water Solubility, LogSw

-2.30

Polar Surface Area

50.437

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

5.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

72.22

P510-0221 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P510-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P510-0221?
Check Price and Availability of P510-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P510-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P510-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P510-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P510-0221 available by request