P510-1088 Screening compound: 1-[6-(piperidin-1-yl)pyrimidin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Chemical Structure Depiction of ChemDiv screening compound P510-1088
1-[6-(piperidin-1-yl)pyrimidin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P510-1088

Molecular Formula

C₂₁H₂₈N₆O (C21 H28 N6 O)

Compound Name

1-[6-(piperidin-1-yl)pyrimidin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-[6-(piperidin-1-yl)pyrimidin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ncnc(N2CCCCC2)c1)NCc1ncccc1

InChI

InChI=1S/C21H28N6O/c28-21(23-15-18-6-2-3-9-22-18)17-7-12-27(13-8-17)20-14-19(24-16-25-20)26-10-4-1-5-11-26/h2-3,6,9,14,16-17H,1,4-5,7-8,10-13,15H2,(H,23,28)

InChI Key

JIJPULMAGPLPOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27577883

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

3.020

Distribution Coefficient, logD

3.016

Water Solubility, LogSw

-3.12

Polar Surface Area

59.837

Acid Dissociation Constant (pK_a)

12.37

Base Dissociation Constant (pK_b)

5.29

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

52.40

P510-1088 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Hemic and lymphatic
Cardiovascular
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Male
Female
Hemic and lymphatic
Skin
Infections
Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Cardiovascular
Skin
Metabolic
Immune system
Cancer
Digestive system
Female
Hemic and lymphatic
Metabolic
Immune system
Nervous system
Cardiovascular

Mechanism of action:

PPI modulators
PPI modulators

Structure:

Mimetics
Cyclic compounds

Targets:

Kinases
Proteases
Others
Ion Channels

References: we are preparing a list of scientific research reports with P510-1088 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P510-1088?
Check Price and Availability of P510-1088, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of P510-1088 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for P510-1088
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for P510-1088

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P510-1088 available by request