P510-2058 Screening compound: 1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

P510-2058 Screening compound: 1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide
P510-2058 Screening compound: 1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P510-2058
1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P510-2058

Molecular Formula

C23H26N6O (C23 H26 N6 O)

Compound Name

1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-{6-[(4-methylphenyl)amino]pyrimidin-4-yl}-N-[(pyridin-4-yl)methyl]piperidine-4-carboxamide

SMILES

Cc(cc1)ccc1Nc1cc(N(CC2)CCC2C(NCc2ccncc2)=O)ncn1

InChI

InChI=1S/C23H26N6O/c1-17-2-4-20(5-3-17)28-21-14-22(27-16-26-21)29-12-8-19(9-13-29)23(30)25-15-18-6-10-24-11-7-18/h2-7,10-11,14,16,19H,8-9,12-13,15H2,1H3,(H,25,30)(H,26,27,28)

InChI Key

YLWBNTWFXRKSED-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27577931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.218

Distribution Coefficient, logD

3.164

Water Solubility, LogSw

-3.09

Polar Surface Area

66.285

Acid Dissociation Constant (pKa)

13.00

Base Dissociation Constant (pKb)

6.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

P510-2058 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with P510-2058 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P510-2058?
Check Price and Availability of P510-2058, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P510-2058 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P510-2058
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P510-2058
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P510-2058 available by request