P558-0118 Screening compound: 8-[(6-fluoroimidazo[1,2-a]pyridin-2-yl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane

P558-0118 Screening compound: 8-[(6-fluoroimidazo[1,2-a]pyridin-2-yl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane
P558-0118 Screening compound: 8-[(6-fluoroimidazo[1,2-a]pyridin-2-yl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P558-0118
8-[(6-fluoroimidazo[1,2-a]pyridin-2-yl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P558-0118

Molecular Formula

C15H18FN3O2 (C15 H18 FN3 O2)

Compound Name

8-[(6-fluoroimidazo[1,2-a]pyridin-2-yl)methyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-({6-fluoroimidazo[12-a]pyridin-2-yl}methyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

Fc(cc1)cn2c1nc(CN(CC1)CCC11OCCO1)c2

InChI

InChI=1S/C15H18FN3O2/c16-12-1-2-14-17-13(11-19(14)9-12)10-18-5-3-15(4-6-18)20-7-8-21-15/h1-2,9,11H,3-8,10H2

InChI Key

WXLSMSZORZMIKB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27604371

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

291.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.622

Distribution Coefficient, logD

-0.274

Water Solubility, LogSw

-1.73

Polar Surface Area

28.463

Acid Dissociation Constant (pKa)

27.17

Base Dissociation Constant (pKb)

9.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.33

P558-0118 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P558-0118 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P558-0118?
Check Price and Availability of P558-0118, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P558-0118 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P558-0118
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P558-0118
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P558-0118 available by request