P578-0130 Screening compound: 4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine

P578-0130 Screening compound: 4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine
P578-0130 Screening compound: 4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound P578-0130
4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P578-0130

Molecular Formula

C18H24N6O2 (C18 H24 N6 O2)

Compound Name

4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine

IUPAC name

4-{1-[6-(4-methylpiperidin-1-yl)pyrimidin-4-yl]-1H-imidazole-4-carbonyl}morpholine

SMILES

CC(CC1)CCN1c1cc(-n2cnc(C(N3CCOCC3)=O)c2)ncn1

InChI

InChI=1S/C18H24N6O2/c1-14-2-4-22(5-3-14)16-10-17(20-12-19-16)24-11-15(21-13-24)18(25)23-6-8-26-9-7-23/h10-14H,2-9H2,1H3

InChI Key

FGARLAZZXQBVMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27605342

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.484

Distribution Coefficient, logD

2.483

Water Solubility, LogSw

-2.44

Polar Surface Area

59.223

Acid Dissociation Constant (pKa)

22.43

Base Dissociation Constant (pKb)

4.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

P578-0130 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P578-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P578-0130?
Check Price and Availability of P578-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P578-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P578-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P578-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P578-0130 available by request