P578-2010 Screening compound: 4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine

P578-2010 Screening compound: 4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine
P578-2010 Screening compound: 4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound P578-2010
4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P578-2010

Molecular Formula

C23H27N7OS (C23 H27 N7 OS)

Compound Name

4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine

IUPAC name

4-(6-{4-[4-(3-methylphenyl)piperazine-1-carbonyl]-1H-imidazol-1-yl}pyrimidin-4-yl)thiomorpholine

SMILES

Cc1cccc(N(CC2)CCN2C(c(nc2)cn2-c2cc(N3CCSCC3)ncn2)=O)c1

InChI

InChI=1S/C23H27N7OS/c1-18-3-2-4-19(13-18)27-5-7-29(8-6-27)23(31)20-15-30(17-26-20)22-14-21(24-16-25-22)28-9-11-32-12-10-28/h2-4,13-17H,5-12H2,1H3

InChI Key

WIDRYERRMIAXOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22596827

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.815

Distribution Coefficient, logD

3.809

Water Solubility, LogSw

-3.68

Polar Surface Area

54.574

Acid Dissociation Constant (pKa)

23.11

Base Dissociation Constant (pKb)

5.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

P578-2010 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P578-2010 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P578-2010?
Check Price and Availability of P578-2010, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P578-2010 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P578-2010
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P578-2010
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P578-2010 available by request