P605-0045 Screening compound: 1-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one

P605-0045 Screening compound: 1-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one
P605-0045 Screening compound: 1-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P605-0045
1-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P605-0045

Molecular Formula

C22H24N4OS (C22 H24 N4 OS)

Compound Name

1-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one

IUPAC name

1-{4-[5-(4-methyl-13-thiazol-2-yl)pyridin-2-yl]piperazin-1-yl}-2-(4-methylphenyl)ethan-1-one

SMILES

Cc1csc(-c(cc2)cnc2N(CC2)CCN2C(Cc2ccc(C)cc2)=O)n1

InChI

InChI=1S/C22H24N4OS/c1-16-3-5-18(6-4-16)13-21(27)26-11-9-25(10-12-26)20-8-7-19(14-23-20)22-24-17(2)15-28-22/h3-8,14-15H,9-13H2,1-2H3

InChI Key

XNDBYEIHURYJLZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27606250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.325

Distribution Coefficient, logD

3.805

Water Solubility, LogSw

-4.13

Polar Surface Area

37.761

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

7.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

P605-0045 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P605-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P605-0045?
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What is the minimum amount of P605-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P605-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P605-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P605-0045 available by request