P605-0152 Screening compound: 2-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole

P605-0152 Screening compound: 2-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole
P605-0152 Screening compound: 2-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound P605-0152
2-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P605-0152

Molecular Formula

C22H21N5OS (C22 H21 N5 OS)

Compound Name

2-{4-[5-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole

IUPAC name

2-{4-[5-(4-methyl-13-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}-1H-indole

SMILES

Cc1csc(-c(cc2)cnc2N(CC2)CCN2C(c2cc(cccc3)c3[nH]2)=O)n1

InChI

InChI=1S/C22H21N5OS/c1-15-14-29-21(24-15)17-6-7-20(23-13-17)26-8-10-27(11-9-26)22(28)19-12-16-4-2-3-5-18(16)25-19/h2-7,12-14,25H,8-11H2,1H3

InChI Key

SVSDSRWMWFPPEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27606287

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.616

Distribution Coefficient, logD

4.095

Water Solubility, LogSw

-4.57

Polar Surface Area

47.637

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

7.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.73

P605-0152 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Cyclic compounds
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P605-0152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P605-0152?
Check Price and Availability of P605-0152, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P605-0152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P605-0152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P605-0152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P605-0152 available by request