P605-0447 Screening compound: 1-(3-chlorobenzoyl)-4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine

P605-0447 Screening compound: 1-(3-chlorobenzoyl)-4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine
P605-0447 Screening compound: 1-(3-chlorobenzoyl)-4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P605-0447
1-(3-chlorobenzoyl)-4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P605-0447

Molecular Formula

C21H21ClN4OS (C21 H21 ClN4 OS)

Compound Name

1-(3-chlorobenzoyl)-4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine

IUPAC name

1-(3-chlorobenzoyl)-4-[5-(45-dimethyl-13-thiazol-2-yl)pyridin-2-yl]piperazine

SMILES

Cc1c(C)sc(-c(cc2)cnc2N(CC2)CCN2C(c2cccc(Cl)c2)=O)n1

InChI

InChI=1S/C21H21ClN4OS/c1-14-15(2)28-20(24-14)17-6-7-19(23-13-17)25-8-10-26(11-9-25)21(27)16-4-3-5-18(22)12-16/h3-7,12-13H,8-11H2,1-2H3

InChI Key

FYJHSAWDGCLLEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27606329

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.94

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.606

Distribution Coefficient, logD

3.460

Water Solubility, LogSw

-4.70

Polar Surface Area

39.059

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

P605-0447 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P605-0447 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P605-0447?
Check Price and Availability of P605-0447, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P605-0447 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P605-0447
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P605-0447
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P605-0447 available by request