P605-0459 Screening compound: 1-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine

P605-0459 Screening compound: 1-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine
P605-0459 Screening compound: 1-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P605-0459
1-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P605-0459

Molecular Formula

C19H20N4OS2 (C19 H20 N4 OS2)

Compound Name

1-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine

IUPAC name

1-[5-(45-dimethyl-13-thiazol-2-yl)pyridin-2-yl]-4-(thiophene-2-carbonyl)piperazine

SMILES

Cc1c(C)sc(-c(cc2)cnc2N(CC2)CCN2C(c2cccs2)=O)n1

InChI

InChI=1S/C19H20N4OS2/c1-13-14(2)26-18(21-13)15-5-6-17(20-12-15)22-7-9-23(10-8-22)19(24)16-4-3-11-25-16/h3-6,11-12H,7-10H2,1-2H3

InChI Key

KYOCAXRQQZVEBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27606332

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.163

Distribution Coefficient, logD

3.017

Water Solubility, LogSw

-3.99

Polar Surface Area

40.077

Acid Dissociation Constant (pKa)

24.77

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

P605-0459 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P605-0459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P605-0459?
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What is the minimum amount of P605-0459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P605-0459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P605-0459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P605-0459 available by request