P605-0518 Screening compound: 1-{4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline

P605-0518 Screening compound: 1-{4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline
P605-0518 Screening compound: 1-{4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound P605-0518
1-{4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P605-0518

Molecular Formula

C24H23N5OS (C24 H23 N5 OS)

Compound Name

1-{4-[5-(4,5-dimethyl-1,3-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline

IUPAC name

1-{4-[5-(45-dimethyl-13-thiazol-2-yl)pyridin-2-yl]piperazine-1-carbonyl}isoquinoline

SMILES

Cc1c(C)sc(-c(cc2)cnc2N(CC2)CCN2C(c2nccc3ccccc23)=O)n1

InChI

InChI=1S/C24H23N5OS/c1-16-17(2)31-23(27-16)19-7-8-21(26-15-19)28-11-13-29(14-12-28)24(30)22-20-6-4-3-5-18(20)9-10-25-22/h3-10,15H,11-14H2,1-2H3

InChI Key

VFJVQAQMTWLKIR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27606352

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.329

Distribution Coefficient, logD

3.183

Water Solubility, LogSw

-4.07

Polar Surface Area

48.606

Acid Dissociation Constant (pKa)

24.77

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

P605-0518 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P605-0518 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P605-0518?
Check Price and Availability of P605-0518, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P605-0518 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P605-0518
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P605-0518
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P605-0518 available by request