P621-1378 Screening compound: 4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

P621-1378 Screening compound: 4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
P621-1378 Screening compound: 4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P621-1378
4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P621-1378

Molecular Formula

C23H27FN4O3 (C23 H27 FN4 O3)

Compound Name

4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one

IUPAC name

4-butyl-2-[4-(2-fluorophenyl)piperazine-1-carbonyl]-2-methyl-2H3H4H-pyrido[32-b][14]oxazin-3-one

SMILES

CCCCN1c(nccc2)c2OC(C)(C(N(CC2)CCN2c(cccc2)c2F)=O)C1=O

InChI

InChI=1S/C23H27FN4O3/c1-3-4-12-28-20-19(10-7-11-25-20)31-23(2,22(28)30)21(29)27-15-13-26(14-16-27)18-9-6-5-8-17(18)24/h5-11H,3-4,12-16H2,1-2H3/t23-/m0/s1

InChI Key

RKAUAAFMGDXQNJ-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27607183

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.664

Distribution Coefficient, logD

3.664

Water Solubility, LogSw

-3.78

Polar Surface Area

52.510

Acid Dissociation Constant (pKa)

25.99

Base Dissociation Constant (pKb)

2.47

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

P621-1378 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P621-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P621-1378?
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What is the minimum amount of P621-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P621-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P621-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P621-1378 available by request