P627-0242 Screening compound: 1-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one

P627-0242 Screening compound: 1-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one
P627-0242 Screening compound: 1-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P627-0242
1-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P627-0242

Molecular Formula

C18H22N4O5 (C18 H22 N4 O5)

Compound Name

1-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one

IUPAC name

1-(2-{14-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-5-(5-ethyl-134-oxadiazol-2-yl)-12-dihydropyridin-2-one

SMILES

CCc1nnc(C(C=C2)=CN(CC(N(CC3)CCC33OCCO3)=O)C2=O)o1

InChI

InChI=1S/C18H22N4O5/c1-2-14-19-20-17(27-14)13-3-4-15(23)22(11-13)12-16(24)21-7-5-18(6-8-21)25-9-10-26-18/h3-4,11H,2,5-10,12H2,1H3

InChI Key

LNONFMITQWGZBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27607250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

-0.650

Distribution Coefficient, logD

-0.650

Water Solubility, LogSw

-0.02

Polar Surface Area

77.760

Acid Dissociation Constant (pKa)

25.21

Base Dissociation Constant (pKb)

-0.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

P627-0242 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P627-0242 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P627-0242?
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What is the minimum amount of P627-0242 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P627-0242
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P627-0242
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P627-0242 available by request