P635-0218 Screening compound: 1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one

P635-0218 Screening compound: 1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one
P635-0218 Screening compound: 1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P635-0218
1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P635-0218

Molecular Formula

C22H23N3O5 (C22 H23 N3 O5)

Compound Name

1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one

IUPAC name

1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-(2-hydroxy-6-methoxyquinolin-3-yl)propan-1-one

SMILES

COc(cc1cc2CCC(N(CC3)CCN3C(c3ccco3)=O)=O)ccc1nc2O

InChI

InChI=1S/C22H23N3O5/c1-29-17-5-6-18-16(14-17)13-15(21(27)23-18)4-7-20(26)24-8-10-25(11-9-24)22(28)19-3-2-12-30-19/h2-3,5-6,12-14H,4,7-11H2,1H3,(H,23,27)

InChI Key

OSLDUZSZSSBMIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27608110

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.865

Distribution Coefficient, logD

1.856

Water Solubility, LogSw

-2.28

Polar Surface Area

74.229

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

3.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

P635-0218 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P635-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P635-0218?
Check Price and Availability of P635-0218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P635-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P635-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P635-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P635-0218 available by request