P635-0364 Screening compound: 3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-1,4-diazepan-1-yl]propan-1-one

P635-0364 Screening compound: 3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-1,4-diazepan-1-yl]propan-1-one
P635-0364 Screening compound: 3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-1,4-diazepan-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P635-0364
3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-1,4-diazepan-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P635-0364

Molecular Formula

C22H25N5O2 (C22 H25 N5 O2)

Compound Name

3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-1,4-diazepan-1-yl]propan-1-one

IUPAC name

3-(2-hydroxy-7-methylquinolin-3-yl)-1-[4-(pyrimidin-2-yl)-14-diazepan-1-yl]propan-1-one

SMILES

Cc1ccc(cc(CCC(N(CCC2)CCN2c2ncccn2)=O)c(O)n2)c2c1

InChI

InChI=1S/C22H25N5O2/c1-16-4-5-17-15-18(21(29)25-19(17)14-16)6-7-20(28)26-10-3-11-27(13-12-26)22-23-8-2-9-24-22/h2,4-5,8-9,14-15H,3,6-7,10-13H2,1H3,(H,25,29)

InChI Key

AGLOKSSTUVDSHQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27608243

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.095

Distribution Coefficient, logD

3.089

Water Solubility, LogSw

-2.91

Polar Surface Area

63.604

Acid Dissociation Constant (pKa)

9.27

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

P635-0364 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P635-0364 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P635-0364?
Check Price and Availability of P635-0364, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P635-0364 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P635-0364
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P635-0364
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P635-0364 available by request