P636-0365 Screening compound: 1-(1-benzyl-6-oxo-1,6-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide

P636-0365 Screening compound: 1-(1-benzyl-6-oxo-1,6-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide
P636-0365 Screening compound: 1-(1-benzyl-6-oxo-1,6-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P636-0365
1-(1-benzyl-6-oxo-1,6-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P636-0365

Molecular Formula

C24H27N5O2 (C24 H27 N5 O2)

Compound Name

1-(1-benzyl-6-oxo-1,6-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-(1-benzyl-6-oxo-16-dihydropyridazin-4-yl)-N-[2-(pyridin-2-yl)ethyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1C(C=NN1Cc2ccccc2)=CC1=O)NCCc1ncccc1

InChI

InChI=1S/C24H27N5O2/c30-23-16-22(17-27-29(23)18-19-6-2-1-3-7-19)28-14-10-20(11-15-28)24(31)26-13-9-21-8-4-5-12-25-21/h1-8,12,16-17,20H,9-11,13-15,18H2,(H,26,31)

InChI Key

YMBMWUMMLNKNBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27608496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.777

Distribution Coefficient, logD

1.540

Water Solubility, LogSw

-2.23

Polar Surface Area

66.291

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

5.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P636-0365 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P636-0365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P636-0365?
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What is the minimum amount of P636-0365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P636-0365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P636-0365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P636-0365 available by request