P637-0148 Screening compound: N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide

P637-0148 Screening compound: N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide
P637-0148 Screening compound: N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P637-0148
N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P637-0148

Molecular Formula

C22H26N4O4 (C22 H26 N4 O4)

Compound Name

N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide

IUPAC name

N-(6-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy}pyridin-3-yl)cyclopropanecarboxamide

SMILES

COc1cccc(N(CC2)CCN2C(COc(cc2)ncc2NC(C2CC2)=O)=O)c1

InChI

InChI=1S/C22H26N4O4/c1-29-19-4-2-3-18(13-19)25-9-11-26(12-10-25)21(27)15-30-20-8-7-17(14-23-20)24-22(28)16-5-6-16/h2-4,7-8,13-14,16H,5-6,9-12,15H2,1H3,(H,24,28)

InChI Key

TXXXKHDENFUPDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27608618

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.454

Distribution Coefficient, logD

2.454

Water Solubility, LogSw

-2.88

Polar Surface Area

67.315

Acid Dissociation Constant (pKa)

11.98

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

P637-0148 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P637-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P637-0148?
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What is the minimum amount of P637-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P637-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P637-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P637-0148 available by request