P637-0228 Screening compound: N-[6-({[1-(3,4-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide

P637-0228 Screening compound: N-[6-({[1-(3,4-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide
P637-0228 Screening compound: N-[6-({[1-(3,4-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P637-0228
N-[6-({[1-(3,4-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P637-0228

Molecular Formula

C21H25N3O5 (C21 H25 N3 O5)

Compound Name

N-[6-({[1-(3,4-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide

IUPAC name

N-[6-({[1-(34-dimethoxyphenyl)ethyl]carbamoyl}methoxy)pyridin-3-yl]cyclopropanecarboxamide

SMILES

CC(c(cc1)cc(OC)c1OC)NC(COc(cc1)ncc1NC(C1CC1)=O)=O

InChI

InChI=1S/C21H25N3O5/c1-13(15-6-8-17(27-2)18(10-15)28-3)23-19(25)12-29-20-9-7-16(11-22-20)24-21(26)14-4-5-14/h6-11,13-14H,4-5,12H2,1-3H3,(H,23,25)(H,24,26)/t13-/m0/s1

InChI Key

BSPIIAQJQNZLSC-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD27608676

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.576

Distribution Coefficient, logD

2.576

Water Solubility, LogSw

-3.01

Polar Surface Area

79.014

Acid Dissociation Constant (pKa)

11.98

Base Dissociation Constant (pKb)

3.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

P637-0228 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with P637-0228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P637-0228?
Check Price and Availability of P637-0228, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P637-0228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P637-0228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P637-0228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P637-0228 available by request