P657-0724 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)furan-2-sulfonamide

P657-0724 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)furan-2-sulfonamide
P657-0724 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)furan-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P657-0724
5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)furan-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P657-0724

Molecular Formula

C18H17N3O6S (C18 H17 N3 O6 S)

Compound Name

5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)furan-2-sulfonamide

IUPAC name

5-(5-cyclobutyl-134-oxadiazol-2-yl)-N-(23-dihydro-14-benzodioxin-6-yl)furan-2-sulfonamide

SMILES

O=S(c1ccc(-c2nnc(C3CCC3)o2)o1)(Nc(cc1)cc2c1OCCO2)=O

InChI

InChI=1S/C18H17N3O6S/c22-28(23,21-12-4-5-13-15(10-12)25-9-8-24-13)16-7-6-14(26-16)18-20-19-17(27-18)11-2-1-3-11/h4-7,10-11,21H,1-3,8-9H2

InChI Key

TZPYVFIDQCCPFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27609479

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.966

Distribution Coefficient, logD

1.685

Water Solubility, LogSw

-2.70

Polar Surface Area

96.370

Acid Dissociation Constant (pKa)

7.44

Base Dissociation Constant (pKb)

-1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P657-0724 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with P657-0724 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P657-0724?
Check Price and Availability of P657-0724, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P657-0724 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P657-0724
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P657-0724
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P657-0724 available by request