P657-0758 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide

P657-0758 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide
P657-0758 Screening compound: 5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P657-0758
5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P657-0758

Molecular Formula

C18H19N3O5S (C18 H19 N3 O5 S)

Compound Name

5-(5-cyclobutyl-1,3,4-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide

IUPAC name

5-(5-cyclobutyl-134-oxadiazol-2-yl)-N-[(4-methoxyphenyl)methyl]furan-2-sulfonamide

SMILES

COc1ccc(CNS(c2ccc(-c3nnc(C4CCC4)o3)o2)(=O)=O)cc1

InChI

InChI=1S/C18H19N3O5S/c1-24-14-7-5-12(6-8-14)11-19-27(22,23)16-10-9-15(25-16)18-21-20-17(26-18)13-3-2-4-13/h5-10,13,19H,2-4,11H2,1H3

InChI Key

OFKFCSOIGNCUNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27609494

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.43

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.725

Distribution Coefficient, logD

2.725

Water Solubility, LogSw

-3.20

Polar Surface Area

89.199

Acid Dissociation Constant (pKa)

10.67

Base Dissociation Constant (pKb)

-1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P657-0758 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P657-0758 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P657-0758?
Check Price and Availability of P657-0758, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P657-0758 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P657-0758
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P657-0758
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P657-0758 available by request