P658-1018 Screening compound: 1-butyl-4-{[4-(5-cyclopentyl-1,3,4-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine

P658-1018 Screening compound: 1-butyl-4-{[4-(5-cyclopentyl-1,3,4-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine
P658-1018 Screening compound: 1-butyl-4-{[4-(5-cyclopentyl-1,3,4-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P658-1018
1-butyl-4-{[4-(5-cyclopentyl-1,3,4-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P658-1018

Molecular Formula

C19H28N4O4S (C19 H28 N4 O4 S)

Compound Name

1-butyl-4-{[4-(5-cyclopentyl-1,3,4-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine

IUPAC name

1-butyl-4-{[4-(5-cyclopentyl-134-oxadiazol-2-yl)furan-2-yl]sulfonyl}piperazine

SMILES

CCCCN(CC1)CCN1S(c1cc(-c2nnc(C3CCCC3)o2)co1)(=O)=O

InChI

InChI=1S/C19H28N4O4S/c1-2-3-8-22-9-11-23(12-10-22)28(24,25)17-13-16(14-26-17)19-21-20-18(27-19)15-6-4-5-7-15/h13-15H,2-12H2,1H3

InChI Key

VFBRIMXHMYMGIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27609774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.135

Distribution Coefficient, logD

3.019

Water Solubility, LogSw

-3.12

Polar Surface Area

76.700

Acid Dissociation Constant (pKa)

26.07

Base Dissociation Constant (pKb)

6.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

68.40

P658-1018 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P658-1018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P658-1018?
Check Price and Availability of P658-1018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P658-1018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P658-1018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P658-1018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P658-1018 available by request