P659-1911 Screening compound: 8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane

P659-1911 Screening compound: 8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
P659-1911 Screening compound: 8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound P659-1911
8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P659-1911

Molecular Formula

C20H30N6O2 (C20 H30 N6 O2)

Compound Name

8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{[5-methyl-7-(4-methylpiperidin-1-yl)-[124]triazolo[15-a]pyrimidin-2-yl]methyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

CC(CC1)CCN1c1cc(C)nc2nc(CN(CC3)CCC33OCCO3)nn12

InChI

InChI=1S/C20H30N6O2/c1-15-3-7-25(8-4-15)18-13-16(2)21-19-22-17(23-26(18)19)14-24-9-5-20(6-10-24)27-11-12-28-20/h13,15H,3-12,14H2,1-2H3

InChI Key

RECDNRQPISAWPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27609854

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.104

Distribution Coefficient, logD

1.892

Water Solubility, LogSw

-2.14

Polar Surface Area

52.549

Acid Dissociation Constant (pKa)

24.11

Base Dissociation Constant (pKb)

7.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

75.00

P659-1911 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P659-1911 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P659-1911?
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What is the minimum amount of P659-1911 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P659-1911
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P659-1911
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P659-1911 available by request