P667-0014 Screening compound: 1-[5-(5-isoxazolyl)-2,3-dihydro-1H-indol-1-yl]-2-(2-thienyl)-1-ethanone

P667-0014 Screening compound: 1-[5-(5-isoxazolyl)-2,3-dihydro-1H-indol-1-yl]-2-(2-thienyl)-1-ethanone
P667-0014 Screening compound: 1-[5-(5-isoxazolyl)-2,3-dihydro-1H-indol-1-yl]-2-(2-thienyl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P667-0014
1-[5-(5-isoxazolyl)-2,3-dihydro-1H-indol-1-yl]-2-(2-thienyl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P667-0014

Molecular Formula

C17H14N2O2S (C17 H14 N2 O2 S)

Compound Name

1-[5-(5-isoxazolyl)-2,3-dihydro-1H-indol-1-yl]-2-(2-thienyl)-1-ethanone

IUPAC name

n/a

SMILES

O=C(Cc1cccs1)N(CC1)c(cc2)c1cc2-c1ccno1

InChI

InChI=1S/C17H14N2O2S/c20-17(11-14-2-1-9-22-14)19-8-6-12-10-13(3-4-15(12)19)16-5-7-18-21-16/h1-5,7,9-10H,6,8,11H2

InChI Key

FRLUVXBCYNNTCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27610678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

310.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.904

Distribution Coefficient, logD

2.904

Water Solubility, LogSw

-3.40

Polar Surface Area

38.277

Acid Dissociation Constant (pKa)

20.79

Base Dissociation Constant (pKb)

-0.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

P667-0014 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P667-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P667-0014?
Check Price and Availability of P667-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P667-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P667-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P667-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P667-0014 available by request