P667-0046 Screening compound: 5-(1,2-oxazol-5-yl)-1-(thiophene-2-carbonyl)-2,3-dihydro-1H-indole

P667-0046 Screening compound: 5-(1,2-oxazol-5-yl)-1-(thiophene-2-carbonyl)-2,3-dihydro-1H-indole
P667-0046 Screening compound: 5-(1,2-oxazol-5-yl)-1-(thiophene-2-carbonyl)-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound P667-0046
5-(1,2-oxazol-5-yl)-1-(thiophene-2-carbonyl)-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P667-0046

Molecular Formula

C16H12N2O2S (C16 H12 N2 O2 S)

Compound Name

5-(1,2-oxazol-5-yl)-1-(thiophene-2-carbonyl)-2,3-dihydro-1H-indole

IUPAC name

5-(12-oxazol-5-yl)-1-(thiophene-2-carbonyl)-23-dihydro-1H-indole

SMILES

O=C(c1cccs1)N(CC1)c(cc2)c1cc2-c1ccno1

InChI

InChI=1S/C16H12N2O2S/c19-16(15-2-1-9-21-15)18-8-6-11-10-12(3-4-13(11)18)14-5-7-17-20-14/h1-5,7,9-10H,6,8H2

InChI Key

ZPAQEFADUKURQM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27610687

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

296.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.974

Distribution Coefficient, logD

2.974

Water Solubility, LogSw

-3.42

Polar Surface Area

38.805

Acid Dissociation Constant (pKa)

25.58

Base Dissociation Constant (pKb)

-0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

P667-0046 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Fragments Library (11262 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands
Structure:
  • Fragments
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with P667-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P667-0046?
Check Price and Availability of P667-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P667-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P667-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P667-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P667-0046 available by request