P667-0129 Screening compound: 2-(2-methylphenyl)-1-[5-(1,2-oxazol-5-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

P667-0129 Screening compound: 2-(2-methylphenyl)-1-[5-(1,2-oxazol-5-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one
P667-0129 Screening compound: 2-(2-methylphenyl)-1-[5-(1,2-oxazol-5-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P667-0129
2-(2-methylphenyl)-1-[5-(1,2-oxazol-5-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P667-0129

Molecular Formula

C20H18N2O2 (C20 H18 N2 O2)

Compound Name

2-(2-methylphenyl)-1-[5-(1,2-oxazol-5-yl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

IUPAC name

2-(2-methylphenyl)-1-[5-(12-oxazol-5-yl)-23-dihydro-1H-indol-1-yl]ethan-1-one

SMILES

Cc1c(CC(N(CC2)c(cc3)c2cc3-c2ccno2)=O)cccc1

InChI

InChI=1S/C20H18N2O2/c1-14-4-2-3-5-15(14)13-20(23)22-11-9-16-12-17(6-7-18(16)22)19-8-10-21-24-19/h2-8,10,12H,9,11,13H2,1H3

InChI Key

JGXJZZQIUHSYPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27610715

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.110

Distribution Coefficient, logD

4.110

Water Solubility, LogSw

-4.24

Polar Surface Area

37.259

Acid Dissociation Constant (pKa)

16.00

Base Dissociation Constant (pKb)

1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

P667-0129 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with P667-0129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P667-0129?
Check Price and Availability of P667-0129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P667-0129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P667-0129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P667-0129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P667-0129 available by request