P667-0274 Screening compound: 1-[5-(3-METHYL-1,2-OXAZOL-5-YL)-2,3-DIHYDRO-1H-INDOL-1-YL]-2-(2-METHYLPHENYL)ETHAN-1-ONE

P667-0274 Screening compound: 1-[5-(3-METHYL-1,2-OXAZOL-5-YL)-2,3-DIHYDRO-1H-INDOL-1-YL]-2-(2-METHYLPHENYL)ETHAN-1-ONE
P667-0274 Screening compound: 1-[5-(3-METHYL-1,2-OXAZOL-5-YL)-2,3-DIHYDRO-1H-INDOL-1-YL]-2-(2-METHYLPHENYL)ETHAN-1-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound P667-0274
1-[5-(3-METHYL-1,2-OXAZOL-5-YL)-2,3-DIHYDRO-1H-INDOL-1-YL]-2-(2-METHYLPHENYL)ETHAN-1-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P667-0274

Molecular Formula

C21H20N2O2 (C21 H20 N2 O2)

Compound Name

1-[5-(3-METHYL-1,2-OXAZOL-5-YL)-2,3-DIHYDRO-1H-INDOL-1-YL]-2-(2-METHYLPHENYL)ETHAN-1-ONE

IUPAC name

n/a

SMILES

Cc1noc(-c(cc2)cc(CC3)c2N3C(Cc2c(C)cccc2)=O)c1

InChI

InChI=1S/C21H20N2O2/c1-14-5-3-4-6-16(14)13-21(24)23-10-9-17-12-18(7-8-19(17)23)20-11-15(2)22-25-20/h3-8,11-12H,9-10,13H2,1-2H3

InChI Key

HQTZACJLMKITAV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27610736

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.759

Distribution Coefficient, logD

4.759

Water Solubility, LogSw

-4.46

Polar Surface Area

36.731

Acid Dissociation Constant (pKa)

16.00

Base Dissociation Constant (pKb)

1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

P667-0274 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P667-0274 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P667-0274?
Check Price and Availability of P667-0274, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P667-0274 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P667-0274
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P667-0274
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P667-0274 available by request