P680-0580 Screening compound: 7-fluoro-3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-4-hydroxy-1,2-dihydroquinolin-2-one

P680-0580 Screening compound: 7-fluoro-3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-4-hydroxy-1,2-dihydroquinolin-2-one
P680-0580 Screening compound: 7-fluoro-3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-4-hydroxy-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P680-0580
7-fluoro-3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-4-hydroxy-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P680-0580

Molecular Formula

C17H9F2N3O3 (C17 H9 F2 N3 O3)

Compound Name

7-fluoro-3-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-4-hydroxy-1,2-dihydroquinolin-2-one

IUPAC name

7-fluoro-3-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-4-hydroxy-12-dihydroquinolin-2-one

SMILES

OC(c(ccc(F)c1)c1N1)=C(c2nc(-c3cc(F)ccc3)no2)C1=O

InChI

InChI=1S/C17H9F2N3O3/c18-9-3-1-2-8(6-9)15-21-17(25-22-15)13-14(23)11-5-4-10(19)7-12(11)20-16(13)24/h1-7H,(H2,20,23,24)

InChI Key

UKJOYQIWJMESKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27611206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.27

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.036

Distribution Coefficient, logD

-0.938

Water Solubility, LogSw

-3.55

Polar Surface Area

71.593

Acid Dissociation Constant (pKa)

3.43

Base Dissociation Constant (pKb)

-5.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

P680-0580 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P680-0580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P680-0580?
Check Price and Availability of P680-0580, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P680-0580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P680-0580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P680-0580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P680-0580 available by request