P681-0211 Screening compound: N-ethyl-5-methoxy-2-oxo-1,2-dihydro-1'H-spiro[indole-3,3'-pyrrolidine]-1'-carboxamide

P681-0211 Screening compound: N-ethyl-5-methoxy-2-oxo-1,2-dihydro-1'H-spiro[indole-3,3'-pyrrolidine]-1'-carboxamide
P681-0211 Screening compound: N-ethyl-5-methoxy-2-oxo-1,2-dihydro-1'H-spiro[indole-3,3'-pyrrolidine]-1'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P681-0211
N-ethyl-5-methoxy-2-oxo-1,2-dihydro-1'H-spiro[indole-3,3'-pyrrolidine]-1'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P681-0211

Molecular Formula

C15H19N3O3 (C15 H19 N3 O3)

Compound Name

N-ethyl-5-methoxy-2-oxo-1,2-dihydro-1'H-spiro[indole-3,3'-pyrrolidine]-1'-carboxamide

IUPAC name

N-ethyl-5-methoxy-2-oxo-12-dihydrospiro[indole-33'-pyrrolidine]-1'-carboxamide

SMILES

CCNC(N(CC1)CC1(c(cc(cc1)OC)c1N1)C1=O)=O

InChI

InChI=1S/C15H19N3O3/c1-3-16-14(20)18-7-6-15(9-18)11-8-10(21-2)4-5-12(11)17-13(15)19/h4-5,8H,3,6-7,9H2,1-2H3,(H,16,20)(H,17,19)/t15-/m0/s1

InChI Key

QNIITNSLOHPGDX-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27611473

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

289.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.387

Distribution Coefficient, logD

1.387

Water Solubility, LogSw

-2.45

Polar Surface Area

59.742

Acid Dissociation Constant (pKa)

12.51

Base Dissociation Constant (pKb)

-0.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

46.67

P681-0211 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P681-0211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P681-0211?
Check Price and Availability of P681-0211, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P681-0211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P681-0211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P681-0211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P681-0211 available by request