P681-0333 Screening compound: N-(2-fluorophenyl)-1-methyl-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-1'-carboxamide

P681-0333 Screening compound: N-(2-fluorophenyl)-1-methyl-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-1'-carboxamide
P681-0333 Screening compound: N-(2-fluorophenyl)-1-methyl-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-1'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P681-0333
N-(2-fluorophenyl)-1-methyl-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-1'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P681-0333

Molecular Formula

C19H18FN3O2 (C19 H18 FN3 O2)

Compound Name

N-(2-fluorophenyl)-1-methyl-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-1'-carboxamide

IUPAC name

N-(2-fluorophenyl)-1-methyl-2-oxo-12-dihydrospiro[indole-33'-pyrrolidine]-1'-carboxamide

SMILES

CN(C(C1(CC2)CN2C(Nc(cccc2)c2F)=O)=O)c2c1cccc2

InChI

InChI=1S/C19H18FN3O2/c1-22-16-9-5-2-6-13(16)19(17(22)24)10-11-23(12-19)18(25)21-15-8-4-3-7-14(15)20/h2-9H,10-12H2,1H3,(H,21,25)/t19-/m0/s1

InChI Key

NYRKIZYLYXZHJH-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27611578

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.638

Distribution Coefficient, logD

2.638

Water Solubility, LogSw

-3.43

Polar Surface Area

40.544

Acid Dissociation Constant (pKa)

11.58

Base Dissociation Constant (pKb)

-1.07

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

P681-0333 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Aging Library (44940 compounds)

Hsp90-Targeted Library (11355 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with P681-0333 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P681-0333?
Check Price and Availability of P681-0333, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P681-0333 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P681-0333
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P681-0333
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P681-0333 available by request