P682-1227 Screening compound: N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

P682-1227 Screening compound: N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
P682-1227 Screening compound: N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P682-1227
N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P682-1227

Molecular Formula

C24H20FN3O3 (C24 H20 FN3 O3)

Compound Name

N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

N-[(4-ethylphenyl)methyl]-1-(3-fluorophenyl)-4-hydroxy-2-oxo-12-dihydro-18-naphthyridine-3-carboxamide

SMILES

CCc1ccc(CNC(C(C(N(c2cccc(F)c2)c2ncccc22)=O)=C2O)=O)cc1

InChI

InChI=1S/C24H20FN3O3/c1-2-15-8-10-16(11-9-15)14-27-23(30)20-21(29)19-7-4-12-26-22(19)28(24(20)31)18-6-3-5-17(25)13-18/h3-13,29H,2,14H2,1H3,(H,27,30)

InChI Key

SOIHBIJJSFTSFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27611902

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.324

Distribution Coefficient, logD

0.376

Water Solubility, LogSw

-3.55

Polar Surface Area

64.545

Acid Dissociation Constant (pKa)

4.45

Base Dissociation Constant (pKb)

-3.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

P682-1227 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P682-1227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P682-1227?
Check Price and Availability of P682-1227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P682-1227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P682-1227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P682-1227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P682-1227 available by request